At All American Pharmaceutical, we’re committed to validating every ingredient through rigorous science. That’s why we conducted this Taxadrol testosterone study across two species—rats and humans—to understand how this natural botanical blend supports healthy testosterone levels. The results, including positive increases in human subjects, demonstrate Taxadrol®’s potential as a powerful tool for men’s health and athletic performance formulations.
The Effect of a Natural Compound (Taxadrol®) On Testosterone Levels In Two Species
Jeff Golini, Ph.D.
All American Pharmaceutical, Billings, Montana
Background
Taxadrol® is a mixture of botanical extracts derived from several all-natural plant sources. These extracts are believed to act by either suppressing estrogen production/transformation or encouraging the production of male hormone precursors. Increased testosterone production has been observed across species, including male Wistar rats and men. This cross-species consistency strengthens the evidence for Taxadrol®’s mechanism of action.
Study Objective
The study was conducted to assess the short-term benefits and potential side effects of Taxadrol® in rats and humans. This study was also intended to provide information on the potential
health benefits and side effects of Taxadrol® for athletes, or any male suffering from low testosterone levels.
Materials and Method
A total of 160 male Wistar rats were randomly assigned to 16 treatment groups. Taxadrol treatment ranged from 4 mg/kg to 16 mg/kg, twice daily, via the oral route using a gastric tube. The treatment period ranged from 10 to 31 days across groups. Animals were sacrificed, and blood samples were assayed for testosterone levels at the close of the treatment period.
A total of three human male participants self-administered Taxadrol at a dose of 30 mg, once to three times daily, sublingually. Testosterone levels were measured before the initiation of the
study and at its close.
Results
Following a 17-day treatment period, there was a significant increase in total testosterone levels in animals treated with the lower doses (4 and 8 mg/kg, twice daily). In animals treated with 8 mg/kg/twice daily, testosterone levels—both free and total—remained higher vs. the control group even after abstaining for 7 days. This sustained elevation suggests lasting physiological benefits beyond acute supplementation.
All human subjects experienced dramatic increases in testosterone levels (up to 180%). Improvements were noted in strength, endurance, libido, body weight, and body fat. No side effects were reported, but a slight increase in aggressiveness was noted. Serum Albumin and C-reactive protein levels remained within the normal range. These markers confirm that the observed benefits occurred without systemic inflammation or liver stress.
Summary
Taxadrol® exerts modulating effects on testosterone levels in the rat and in man. Short-term use, at the dosages tested, is not associated with toxicity.
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