Studies & Information
- Kre-Celazine Informational Video
- Published Study in Liebert
- Published Study in JANA
- Orphan Drug Status
- Kre-Celazine Introduction
- Kre-Celazine Trifold
- Kre-Celazine Report
- Kre-Celazine Tumor
- Double Blind Study
- Single Trial Study
- Toxicity Study
- Case Study
The following conditions have one thing in common:
- Heart Disease
- Autoimmune Disorder
All of these conditions effect different parts of the body, yet still have something very serious in common: inflammation. Each year, scientists find more and more conditions that inflammation is thought to play a key roll in.
What is inflammation?
Inflammation is our body’s first reaction to infection. When a person gets a cut, for instance (which damages the tissue), those dreaded invaders (called bacteria) enter the body, and the immune system kicks in immediately. This defense mode sends out many different types of specialized immune cells. Each cell has a different job. Mast cells release histidine and cytokines which alert your body of the damage. Histidine’s main job is to increase blood flow to this damaged area which is what causes the redness and swelling. Cells found in the connective tissue and epidermis of the skin, called macrophages (commonly called large eating cells), then enter into the area. Macrophages’ job is to secrete immune messenger that destroys the bacteria, cleaning up the damaged area. The final process is for the cavalry of immune cells to enter the infected area to help with the battle, followed by more cells which begin the healing process.
During this healing process, the area will become red, hot, swollen, and usually very painful. What causes this?
Redness: increased blood flow to the area Hotness: the battle taking place to kill bacteria and heal the area Swollen: excess fluid and cells at the site Pain: the indicator of inflammation
Common causes of inflammation that people experience where the skin becomes hot to the touch, swollen, and painful include a sunburn, a twisted ankle, or an insect bite.
Remember, inflammation is our body’s way of notifying us that there is damage and most importantly, the way our defense keeps invaders from entering our body and causing serious injury. Keep in mind that if this inflammation becomes chronic or low grade, our immune cells stay active which can cause serious damage to good tissue. If this chronic inflamation is left unresolved, it will create other disease; leading to a very painful and damaging inflamed state, attacking the joints, organs, or arteries.What causes inflammation?
As discussed previously, inflammation is an effective method of ensuring that invaders do not enter our bodies and create problems. Invaders can enter from such things as a cut or sunburn.
But outward origins like stress, parasites, viruses, bacteria, environmental poisons, sugar, over eating (obesity), smoking and high blood insulin are just a few other causes of inflammation. There is also a variety of foods that can promote inflammation. Foods that are high in arachidonic acid, like eggs, beef, dairy products, and organ meats (liver, heart and giblets) are great inflamation promoters. The body has a very complicated process that breaks down this arachidonic acid into inflammatory agents, including prostaglandin and leukotriens (hormones) which control the mechanisms of inflammation by constricting blood vessels and promoting blood clots.
Foods that are over-cooked or fried at high temperatures also incite the inflammatory response. This response is due to AGES (Advanced Glycation End Products) which the body sometimes treats as a invader. These AGES are produced when protein is bound to a glucose molecule, and are very difficult for the body to break down. As the body attempts to do so, immune cells secrete large amounts of inflammatory cytokines, which act in the same way they would against an infection. A lot of the diseases occurring today which are contributed to old age, are actually caused by this process. Depending on where the AGES occur, arthritics, cataracts, memory loss, heart disease, or wrinkled skin could result.
So as you can see, inflamation can be positive, preventing the spread of bacteria throughout the body; or negative, leading to AGES and possibly arthritics, caused by actions like over-cooking your food.Conventional Treatments for Inflammation
The pharmaceutical industry has many different types of drugs that merely mask the symptoms or decrease the pain for a short period of time. Research is under way to develop different types of drugs that could actually inhibit the inflammatory process. But as with any drug, there comes a variety of unwanted side effects, etc. Of course, you taking pain killers to relieve the pain is an option, but once again this is simply masking and not preventing or curing the problem.
The main goal of the pharmaceutical industry thus far has been to develop drugs which control the pain. This over-the-counter pain control market saw North Americans alone spend over 3.9 billion dollars in 2005. Acetaminophen was the most popular followed by ibuprofen and then good old aspirin. As a matter of record, more pain medications are purchased for arthritics than any other disorder.
These NSAIDs (non-steroidal anti-inflammatory drugs) do come with a price, however. When taken in higher doses they cause liver damage and kidney failure. Statistics have shown long term use of NSAIDs to cause over 20,000 deaths in the USA annually. In addition to this, over 121,000 North Americans are hospitalized each year from side effects such as gastrointestinal complications (bleeding, nausea, vomiting), liver damage, stomach ulcers, immune system depression, mental confusion, and finally, kidney failure.
Some of the more famous advertised arthritic drugs, have more side effects than letters in the Greek alphabet. This is just what we need, to mask one pain and come up with 10 other aliments that are side effects to these dangerous drugs.Natural Remedies
There are many natural remedies that can be found all throughout local health food stores. Some are just O.K., and most are a waist of money. They usually come with a lot of hype and marketing, but when you try them, they do absolutely nothing to help with inflammation or pain. Glucosamine products have been shown to provide some relief, but this compound must be taken in high dosages. At these higher dosages, Glucosamine has been shown to raise blood sugar levels; another unwanted side effect. With the natural foods market being so unregulated, unless you know for sure that a supplement company does extensive in-house testing, who knows what you as a consumer may be ingesting? I can guarantee that the company that produced it doesn’t have a clue.What is Kre-Celazine® ?
Kre-Celazine® is a “non-drug” patented ingredient that has been medically and clinically proven to reduce pain and rapidly promote joint health, improving flexibility and mobility along with reducing inflamation. Kre-Celazine® is a complex material consisting of bonding Kre-Alkalyn® (US Patent 6,399,661) with esterified fatty acid carbons. The esterifying process makes the fatty acid stable so it does not react with oxygen. (This is not esterified creatine, the fatty acids have be esterified). Inflammation can shorten our life span by promoting many degenerative diseases, so the benefits of Kre-Celazine® are essential to reduce this risk.What does Kre-Celazine® do?
Kre-Celazine® is multi functioning, which is unique as to why this compound is so effective.Part 1:
The body is made up of an enormous amount of cells separated into varied types and functions. The cell membrane is the organized structure separating and protecting components in the cell from neighboring cells and the outside world. One of the major components of the cell membrane is structural lipids. These lipids regulate the nutrients, minerals, electrolytes, drugs, and other compounds across the cell membrane. This regulation is very critical to the adequate function and health of the individual cell.
Kre-Celazine® enhances the cell membrane and its integrity for efficient functionality. Kre-Celazine® provides the cell membrane with an ideal blend of lipids to enhance its function. A myriad of body stressors impair and target the cell membrane’s lipids, creating damage to the peak functioning and health of the membrane and cell. This reaction damages the membrane leading to the cell’s demise. Taking oral capsules or applying Kre-Celazine® cream enables the cell membrane to protect the cell and repel the stressors. Kre-Celazine® also assists in perfecting the function or the channeling capabilities of the cell membrane. The result is a more efficient, fluid permeable, and youthful cell membrane.
Loss of cell membrane integrity from internal and external stressors begins a number of rapid aging processes-including uncontrolled or imbalanced inflammations. Inflammation can occur with age, dietary conditions, free radicals, stress, or other insults which stimulate or stiffen cell membranes. This could lead to one or more forms of arthritis (bursitis and tendonitis included); periodontal disease, wrinkles, cardiovascular disease (CVD), rapid aging and many other related maladies. Kre-Celazine® not only halts the cascade of inflammation, but rapidly begins restoring the body on a cumulative basis. Flexibility is restored, pain is eliminated and appearance of wrinkles is reversed. Kre-Celazine® accomplishes these features by enhancing the lipid structure of the cell membrane and converting it to a super-membrane, enabling the cells to rapidly repair and regenerate. This unique enhancement of the cell membrane leads to the multitude of restorative, healing, and age reversing attributes of Kre-Celazine® -including arthritis and inflammatory conditions.Part 2:
Kre-Celazine® also plays a roll in suppressing inflammatory cell function, decreasing cartilage breakdown, triggering of cell death, and like NSAIDs, reducing the inflammatory activities of COX-2 enzyme. This is primarily accomplished by inhibiting arachidonic acid and decreasing the pro-inflammatory effects of other fatty acids. Remember that arachidonic acid is one of the main promoters of the inflammatory cascade of immune factors. Kre-Celazine® also works to reduce the production of the negative immune factor IL-6 and to control the immune factors responsible for inflammation.Part 3:
The esterified fatty acids in Kre-Celazine® are bonded with Kre-Alkalyn® (US Patent 6,399,661), and studies show that Kre-Alkalyn® relieves joint pain & inflammation.
Remember, intense exercise causes inflammation to the muscles. Too much training and too little rest can produce excessive amounts of inflammation, leading to tissue deterioration, impaired immunities, and serious over-training. Research has shown that using Kre-Celazine® containing Kre-Alkalyn® reduces cellular damage and the inflammatory response after exercise.
When a person exercises or tenses a muscle, energy is required for the muscle to function properly. The energy it uses comes from several different sources, but primarily from nutrients obtained from food. These nutrients are broken down by natural processes occurring within the human body. By this process, new compounds are formed which the body uses to develop energy.
One of these compounds is Adenosine Triphosphate (ATP). When muscle energy is needed, ATP is broken down one step further into a chemical called Adenosine Diphosphate (ADP). This process releases energy which is then used by the contracting muscles. Without sufficient ATP, muscles do not perform properly. Muscle can store only limited amounts of ATP. As a result, it has been found that with about 5-10 seconds of muscle exertion, the amount of stored ATP is depleted. This results in muscle failure and fatigue. When this happens, the body tries to restore its immediate source of ATP by borrowing a high energy phosphate from a chemical called Creatine Phosphate (CP). Muscle cells store the chemical, CP, in the same way it stores ATP. If high intensity exercise goes beyond 10 seconds, the body will continue to try and restore its ATP levels by a process called glycolysis. This process is complicated and is a slow method of restoring ATP levels. When the body does not have enough energy to function properly, ailments like inflammation and joint pain can set in (due to lack of recovery). Increased CP levels are essential for recuperation and recovery.Part 4:
One of the key effects that Kre-Celazine® has on the body is its Alkalizing Effects. When considering the many components which make up our health, few things are more important in the body than having the proper pH or alkaline/acid balance. There are different levels of pH in various systems of the body, but they must all be kept in a very specific balance for the body to function normally and at peak efficiency.
The various foods we consume are the primary means by which the body is either kept in optimal pH balance, or thrown into pH chaos. Too many acidic foods, like sodas and processed foods, create a state of severe imbalance in the pH levels (particularly a low pH). Also, many new dietary supplements on the market today contain loads of citric acids for taste, which are at higher levels then seen in foods. The body likes to be slightly on the alkaline side of the scale and will compensate and correct this imbalance. The process of trying to re-establish a normal, healthy pH when altered is very stressful on the body. If sustained for a long enough period of time, this altered pH can result in abnormal organ function, damage, and disease.
The pH scale ranges from 1-14, 1 being the most acidic, and 14 being the most alkaline. The delicate pH range for good health at the cellular level must be maintained within the range of 6.8-7.4 . When you lower your body's pH to the acidic side, immediate problems develop that will eventually result in damage and disease. Besides effecting your body's function, this low pH state has also been show to effect the mind and emotions. The following are some side effects of sustaining your body at a low pH:
- Low grade fevers
- Joint pain & inflammation
- Susceptibility to infection
- Digestive problems
This is just to name a few! The benefits of Kre-Celazine's® patented alkalizing technology are crucial to eliminating inflammation and putting your body in what I like to call the "green house effect". A balanced pH is where your body functions, grows, recovers, and works best.
Kre-Celazine® , with its double patent, is one of the most researched products on the market. Kre-Celazine® is new technology that far surpasses the large doses of glucosamine that are currently needed to get some joint pain relief, by using dangerous drugs that just mask the pain. For optimal results, try Kre-Celazine® capsules along with our joint cream, applied directly to the area that hurts.
Kre-Celazine® is a trademark of All American Pharmaceutical. US Patent 6,399,661 is registered to BioCeuticals Research & Development Analytical Laboratories. Other patents are issued and pending world wide.
Kre-Celazine® as a raw material is manufactured by Rocky Mountain Chemical Company and processed by All American Pharmaceutical.